Lab

Diagnostic evaluation of patients with hyperoxaluria, recurrent kidney stones and/or nephrocalcinosis.

In collaboration with the Wisplinghoff lab we are able to determine both lithogenic (e.g. oxalate, calcium), as well as stone inhibitory substances (e.g. citrate) in urine, but also in plasma samples.

For better diagnostic evaluation of patients with primary hyperoxaluria we additionally offer analysis of glycolate (PH I), as well as L-glyceric acid (PH II) and hydroxy-oxo-glutrate (PH III), again in urine and plasma samples.

Ideally, one or better two-three 24 h urines should be collected and send for analysis. Spot urine samples can be obtained in infants and small children.

Please adhere to the preservation rules and the specific mailing information on our lab sheets.

The molecular genetic diagnostic for the primary hyperoxalurias is done in collaboration with the Institute of Human Genetics Cologne. Mutation analysis can be performed for the currently known three genes:

- AGXT (PH I)
- GRHPR (PH II)
- HOGA1 (PH III)

Instruction for urine collections

Lab request form