Diagnostic evaluation of patients with hyperoxaluria, recurrent kidney stones and/or nephrocalcinosis.

We are able to determine both lithogenic (e.g. oxalate, calcium), as well as stone inhibitory substances (e.g. citrate) in urine, but also in plasma samples.

For better diagnostic evaluation of patients with primary hyperoxaluria we additionally offer analysis of glycolate, as well as L-glyceric acid, again in urine and plasma samples.

Ideally, one or better two-three 24 h urines should be collected and send for analysis. Spot urine samples can be obtained in infants and small children.

Please adhere to the preservation rules and the specific mailing information on our lab sheets.

For stool examination to detect the presence of oxalate degrading bacteria (Oxalobacter formigenes), which is performed in collaboration with the local institute of Microbiology, a spoonful of stool is necessary send by normal mail.

The molecular genetic diagnostic for the primary hyperoxalurias is done in collaboration with the Institute of Human Genetics Cologne. Mutation analysis can be performed for the currently known three genes:


24 h urine analysis for nephrolithiasis patients (pdf)

Plasma oxalate determination (pdf)

24 h urine collections in patients with nephrolithiasis, nephrocalcinosis or hematuria (pdf)